Keanu Reeves

Johnny Mnemonic

Dina Meyer

Jane

Takeshi Kitano

Takahashi

Ice-T

J-Bone

Dolph Lundgren

Street Preacher

Denis Akiyama

Shinji

Henry Rollins

Spider

Barbara Sukowa

Anna Kalmann

Udo Kier

Ralfi

Tracy Tweed

Pretty

Falconer Abraham

Yomamma

Don Francks

Hooky

Diego Chambers

Henson

Sherry Miller

Takahashi's Secretary

Arthur Eng

Viet

Von Flores

Viet

Victoria Tengelis

Pharmakom Receptionist

Warren Sulatycky

Yakuza Operator

Celina Wu

Mikiyo

Jamie Elman

Toad

Simon Sinn

Man in Hotel Lobby

Caitlin Carmody

Twin in Hotel Lobby

Erin Carmody

Twin in Hotel Lobby

Douglas O'Keeffe

Pharmakom Security Officer

Marlow Vella

Lotek Kid

Howard Szafer

Strike

Paul Brogren

Stump

Arthi Sambasivan

Nurse

Michael A. Miranda

Stick

Coyote Shivers

Buddy

Lynne Adams

Yakuza with Rocket Launcher

Michael Shearer

Yakuza Partner

Susan Tsagkaris

Opera Singer

Chris Comrie

Beijing Riot Newscaster

Gene Mack

Laslo

Robin Crosby

Girl in Hotel Room

Glenn Bang

Bandleader (uncredited)

Natalie Gray

Tall Chinese Man (uncredited)