Leonardo DiCaprio

Dr. Randall Mindy

Jennifer Lawrence

Kate Dibiasky

Meryl Streep

President Orlean

Cate Blanchett

Brie Evantee

Rob Morgan

Dr. Teddy Oglethorpe

Jonah Hill

Jason Orlean

Mark Rylance

Peter Isherwell

Tyler Perry

Jack Bremmer

Timothée Chalamet

Yule

Ron Perlman

Benedict Drask

Ariana Grande

Riley Bina

Kid Cudi

DJ Chello

Himesh Patel

Phillip

Melanie Lynskey

June Mindy

Michael Chiklis

Dan Pawketty

Tomer Sisley

Adul Grelio

Paul Guilfoyle

General Themes

Robert Joy

Congressman Tenant

Jack Alberts

Oliver

Ting

Win

Lance A. Williams

Daniel

Shimali de Silva

Nisha

Hettienne Park

Dr. Calder

Rafael Silva

Nasa Scientist

Lonnie Farmer

Old Aide #1

Homa Sarabi-Daunis

White House Office Worker

Barbara Douglass

Office Worker

Rena Maliszewski

Anchor Reporting On Colon

Erik Parillo

Sherriff Conlon

Robert Hurst Radochia

Evan Mindy

Conor Sweeney

Marshall Mindy

Ross Partridge

Keith Ollens

Richard Donelly

Old Aide #2

Liev Schreiber

Bash Narrator (voice)

Samsara Yett

Isherwell Child Aide

Meara Mahoney Gross

Isherwell Child Aide

Jaden Onwuakor

Isherwell Child Aide

Staci Roberts

Linda Dicalio

Wendy Bellevue

Isherwell Child Handler

Mishka Yarovoy

Executive

Chris Everett

Chief Editor Paula Woods

Annette Miller

Mrs. Tanken

Stephen Thorne

Benjamin

Aimee Doherty

Passerby

Natalie Rebenkoff

Talent PA

Gary Tanguay

News Anchor #2

Georgia Lyman

Groomer Thalia

Patricia DeHaney

Hair Person

Ben Sidell

Stage Manager

Therese Plaehn

Autopsy Editor In Charge

Omar Ghonim

Damian

Jody O'Neil

Stage Manager #2

Meghan Leathers

Media Quant

Ashleigh Banfield

Dalia Hensfield

Sarah Silverman

Sarah Benterman

Richard Snee

Senator Lerner

Darryl Wooten

FBI Agent

Danielle Waxman

College Girl

Jeffrey Smith

Blind Man FBI Agent

Jon Glaser

Meow Man

Dorothy Dwyer

Old Tough Lady

Odis Spencer

Chief Justice

Sarah Nolen

Sammy Puppeteer

Alvin Keith

Harrison Telms

Alaina Pinto

American Reporter

Lizzie Short

French Reporter

Juri Love

Japanese Reporter

Sujoy De

Hindi Reporter

Brahms Guignard

Haitian Reporter

Sergei Bushmanov

Russian Reporter

Lewis D. Wheeler

Mission Coordinator

Steve Gagliastro

Onlooker

David J. Curtis

Guy

Kevin Craig West

Secretary of State

Alison Weller

Secretary of Education

Rob Lévesque

Secretary of Interior

Sam Zephir

Captain

Dee Nelson

Dr. Lisa Inez

Beau Allen

Dr. Talcamont

Rebecca Gibel

Waitress

Brian Faherty

Guy from the Bar

Celeste Oliva

Nearby Diner

Amanda Cass

Rioting Patron

Roman Mitichyan

Rioting Patron

Paul Marini

Rioting Patron

Alex Huynh

Rioting Patron

Michael Jibrin

Federal Agent

Bill Mootos

Federal Attorney

Patti Tippo

French President

Allyn Burrows

Mr. Dibiasky

Tori Davis Lawlor

Mrs. Dibiasky

Joy Lang

Housewife

June Holmes

Girl in Commercial

Graham Holmes

Boy in Commercial

Jacob Sanditen

Yule's Friend

Anthony Marrese

Other Friend

Caroline Bergwall

Teen Girl Friend

Anania Williams

Short Guy Friend

Nate Richman

Stocky FBI Agent

Wes Johnson

Don't Look Up'er

John Bucy

Don't Look Up'er

Patrick Gover

Don't Look Up'er

Conrad Perry

Don't Look Up'er

Matt Rouillard

Don't Look Up'er

Christopher Deschenes

Don't Look Up'er

Patrick Michael Strange

Just Look Up'er

J.P. Aaron

Just Look Up'er

Daniela August

Just Look Up'er

Nicholai Senat

Puppet Show Kid

Alexandra Zilch

Puppet Show Kid

Jonathan Kobs

Truthslinger303

Bianca de la Garza

Entertainment Journalist

Caitlin Ishibashi

DJ at Concert

Claire Davis

Bass Player

Elder Isaiah Perez

Organ Player

Coran Spardakis Henley

Drummer

Lance Norris

Loyal Supporter

Ralph M. Studley

Kid Rock Body Double

Frank Ridley

Flight Director

Andrew Haserlat

Mission Tech

Jayne McLendon

Command Tech

Ishaan Khatter

Raghav Manavalan

Khaldoun Rajeh

Egyptian Family

Sheren Rajeh

Egyptian Family

Khaled Rajeh

Egyptian Family

Kareem Rajeh

Egyptian Family

Ahmad Rajeh

Egyptian Family

Adila Rajeh

Egyptian Family

J.T. Turner

Old Billionaire

Ed Peed

Lobbyist

Zach Holmes

#LaunchChallenge MeTuber (uncredited)

Chris Evans

Devin Peters (uncredited)

Marissa Carpio

Reporter with Big Hair (uncredited)

André Silva

Man who looks at the sky (uncredited)