Quvenzhané Wallis

Annie Bennett

Jamie Foxx

William "Will" Stacks

Rose Byrne

Grace Farrell

Cameron Diaz

Miss Colleen Hannigan

Bobby Cannavale

Guy Danlily

Adewale Akinnuoye-Agbaje

Nash

David Zayas

Lou

Amanda Troya

Pepper

Zoe Colletti

Tessie

Nicolette Pierini

Mia

Eden Duncan-Smith

Isabella

Dorian Missick

Annie's "Dad"

Tracie Thoms

Annie's "Mom"

Mike Birbiglia

Social Services Inspector

Stephanie Kurtzuba

Ms. Kovacevic

Peter Van Wagner

Harold Gray

Michael J. Fox

Self

Raushanah Simmons

YaYa L'Occitane

DonnaMarie Recco

Woman on Street

Mila Kunis

Andrea Alvin

Ashton Kutcher

Simon Goodspeed

Rihanna

Moon Goddess

Patricia Clarkson

Focus Group Woman

Sia

Animal Care & Control Volunteer

Bobby Moynihan

Guy In Bar

Pat Kiernan

NY1 Reporter

Beth Rowe

Reporter

Jill Nocolini

Ms. Giannetti

Brad Bong

Pickle Stevens

Andrew Fleming

Cleve Sweetzer

Jessica Sherr

Mary Gillen

Scarlett Benchley

Fish Goddess

Ray Iannicelli

Waiter at Domani

Ty Jones

Stacks Mobile Reporter

Victor Cruz

Teacher

Taylor Richardson

Red Haired "Annie"

Derrick Baskin

Auditioning 'Dad'

Pernell Walker

Auditioning 'Mom'

Lytle Harper

Domani Reporter

J. Kaitlin Becker

Grace's Assistant

Ruby Rose Turner

Orphan #8 (uncredited)

Cynthia Basinet

Wealthy mother (uncredited)

Maesi Caes

Orphan #3 (uncredited)

Josh Elliott Pickel

(uncredited)

Lily Peterson

Tessie Photo Double

Patricia Pinto

Mom

Francesca Pinto

Friend of foster girls

Alan D. Purwin

Stacks' Pilot

Nicholas Pinto

Friend of foster girls

Bill Walters

Soup Kitchen Guest (uncredited)

Amyrh Harris

Classroom Kid

Gabriella Baldacchino

Classmate (uncredited)

Tate McRae

Orphan #17 (uncredited)

Josh Price

Tap Dancing Classmate

Booch O'Connell

Movie Premiere Guest (uncredited)

Aldous Davidson

Biking Guy

Kevin Cannon

Photobomber

Deshane Granger

Waiter

Selina Hamilton

Orphan #2 (uncredited)

Autumn Miller

Orphan #15 (uncredited)

Kaylee Quinn

Orphan #4 (uncredited)

Emma Wetzel

Tap Dancing Classmate