Luke Goss

Carl 'Luke' Lucas / Frankenstein

Ving Rhames

Weyland

Danny Trejo

Goldberg

Tanit Phoenix

Katrina Banks

Dougray Scott

Niles York

Robin Shou

14K

Langley Kirkwood

Dr. Klein

Frederick Koehler

Lists

Tanya van Graan

Amber

Sean Cameron Michael

New Doctor

Hlubi Mboya

Satana

Charlbi Dean

Calimity J

Mark Elderkin

Sgt. Fury

Eugene Khumbanyiwa

Nero

Jeremy Crutchley

Psycho

Yrsa Daley-Ward

Salinas

Ebby Weyime

Maria Rodriguez

Kim Suzanne Engelbrecht

Kelly O' Donnell

Roxane Hayward

Prudence

Bart Fouche

Razor

Michelle van Schaik

Olga Braun

Jesselyn Abrahamse

Silky

Roxane Van Rooyen

Elsa

Shaamilla Noordien

Corns

Gina Athans

Ali

Simone Van Rooyen

Alva Twin

Kim Syster

Olivia

Sylvia Mngxekeza

KP Goldberg Fan Guard

Peter Butler

Executive

Natalie Becker

Pretty Reporter

Quentin Chong

Triad Driver

Irina Miccoli

Weyland's Assistant

Chase Armitage

Apache (archive footage)

Dick Ervasti

Commercial voice (uncredited)

Brandon Livanos

Pretty Boy (uncredited)

Anton David Jeftha

The Jackel (uncredited)