Martin Lawrence

Malcolm Turner / Big Momma

Marisol Nichols

Liliana Morales

Kevin Durand

Oshima

Dan Lauria

Crawford

Kat Dennings

Molly Fuller

Josh Flitter

Stewart

Zachary Levi

Kevin Keneally

Jascha Washington

Trent

Jeanene Fox

Yasmeen

Mark Moses

Tom Fuller

Chloë Grace Moretz

Carrie Fuller

Emily Procter

Leah Fuller

Nia Long

Sherri

Lisa Arrindell

Danielle (as Lisa Arrindell Anderson)

Bryan James Kitto

Trent's Friend

Luke Ramsey

FBI Agent #1

Lonnie Lamont

FBI Agent #2

Marcus Lyle Brown

Erskine

Mehera Blum

Fuller's Secretary, Lucy

Shanna Moakler

Petra

Yuji Okumoto

Parsons

Yvonne Landry

Isabella

Lisa Arrindell

Danielle

Wendy Braun

Coach Bonnie

Ann Mahoney

Coach Lisa

Deneen Tyler

Tassie

Max Van Ville

Chad

Sean Lampkin

Cabbie

William Ragsdale

Bob

Kelly Dowdle

Surf Shop Girl

Jessica White

Bra Model

Amy Morris

Spa Susan

Michelle Parylak

Spa Joanne

Deena Dill

Spa Crystal

Paige Butcher

Background Model

Lucy Wolvert

Background Model

Tim Soergel

Speedo Guy

Jessica Anderson

Bikini Girl

Breanna Startzel

Girl in Bikini

Preston Shores

Andrew

Trevor Shores

Andrew

Sarah Joy Brown

Constance

Adrian Staton

Sandy (uncredited)